News Details
The physical and chemical properties of coating crosslinking agent
2017-4-27 11:52:58
The physical and chemical properties of coating crosslinking agent are very influential in toxicity.For example, if the crosslinking agent is liquid or solid, the toxicity is not the same, the solid is readily attached to the skin, while the liquid has vapor pressure.In general, the chemical activity of crosslinking agent is big, its biomass activity is also strong, easy to cause poison, seem to become law.
The toxicity of crosslinking agents is shown in the following aspects.
Acute toxicity.Typically, LD50 is used.Amines are highly toxic.Most of the organic polyamines have been associated with the fatal respiratory stimulation of the mice with a concentration of about 1000 ~ 12000ug/g, and exposure time 4 ~ 6h.Beramine, secondary amine is more irritating than tertiary, and aromatic amine is more toxic than fatty amine.It is 10 times more toxic than diethylene triamine.Pyridine and piperazine can cause damage to the liver and kidneys, and have a greater systemic toxicity.Acid anhydride crosslinking agent is susceptible to dermatitis and is less toxic.
The stimulation of the skin and the mucosa.The toxic effects of crosslinking agents are more important in the irritation of the skin and the mucosa.Because amine is organic alkali, can dissolve in water and adipose, so also can dissolve in the adipose of skin, soak, cause dermatitis.Prolonged stimulation, which can lead to the disease of generalized hyperdermatitis, the appearance of a spot of erythema, the formation of blisters, cracking, and even the formation of flake flaking, so that the tissue necrosis.Hine and others have conducted detailed research.
Due to the high volatility of the amine, its vapor stimulates the eyes to cause conjunctivitis, tears and the edema of the cornea.Prolonged exposure to high concentrations or high concentrations also has a significant effect on the respiratory tract, causing bronchitis and bronchitis.The acid anhydride class is less irritating to the skin, but its dust is strongly stimulated by the mucous membrane of the respiratory tract such as the eyes and nose and throat, which can cause bronchitis.
The anaphylaxis of the crosslinking agent.So-called allergies, that is, a compound, once the role for human body skin, allergic body formation, in the next or after repeated exposure, not because how much contact, dermatitis can also occur.In this case, the job of the allergy compound should be interrupted.The development of allergy is complicated, the pudding experiment is adopted, the animal is studied.The American plastics industry association (SPI) introduced its own standards.
Chinese name: Diethyl toluene diamine(DETDA)
Diethyltoluenediamine packingļ¼ net weight 200KG/ galvanized iron drum (a small cabinet pallet loaded 16 tons), 1000KG/IB barrels (a small cabinet loaded 18 tons or 23 tons of ISOTANK).
Other toxic effects of crosslinking agents.In addition to the damage of aromatic amine and heterocyclic crosslinking agent to internal organs, the diphenylamine is carcinogenic and has been banned from production and use.Polyphenylenediamine, diamine diphenylsulfone, has been shown to be non-carcinogenic to many toxicologists, and negated the previous view.
The operation of crosslinking agent
1, the toxic low-crosslinking agent replaces the toxicity.
Improve the operating environment, consciously draw the operating area and non-operating area, automate as much as possible, close down, install ventilation and so on.
Strengthen labor protection, use protective glove, clothing and so on, avoid crosslinking agent and skin contact.
The operating area is cleaned in time and kept in good health.
Wash hands in time, face and other foreign skin, if eyes, throat and other organs are harmed, should ask the doctor to handle.
Copyright: Zhang Jia Gang YaRui Chemical co.,Ltd
Diethyl toluene diamine(DETDA) http://www.yaruichem.com
The toxicity of crosslinking agents is shown in the following aspects.
Acute toxicity.Typically, LD50 is used.Amines are highly toxic.Most of the organic polyamines have been associated with the fatal respiratory stimulation of the mice with a concentration of about 1000 ~ 12000ug/g, and exposure time 4 ~ 6h.Beramine, secondary amine is more irritating than tertiary, and aromatic amine is more toxic than fatty amine.It is 10 times more toxic than diethylene triamine.Pyridine and piperazine can cause damage to the liver and kidneys, and have a greater systemic toxicity.Acid anhydride crosslinking agent is susceptible to dermatitis and is less toxic.
The stimulation of the skin and the mucosa.The toxic effects of crosslinking agents are more important in the irritation of the skin and the mucosa.Because amine is organic alkali, can dissolve in water and adipose, so also can dissolve in the adipose of skin, soak, cause dermatitis.Prolonged stimulation, which can lead to the disease of generalized hyperdermatitis, the appearance of a spot of erythema, the formation of blisters, cracking, and even the formation of flake flaking, so that the tissue necrosis.Hine and others have conducted detailed research.
Due to the high volatility of the amine, its vapor stimulates the eyes to cause conjunctivitis, tears and the edema of the cornea.Prolonged exposure to high concentrations or high concentrations also has a significant effect on the respiratory tract, causing bronchitis and bronchitis.The acid anhydride class is less irritating to the skin, but its dust is strongly stimulated by the mucous membrane of the respiratory tract such as the eyes and nose and throat, which can cause bronchitis.
The anaphylaxis of the crosslinking agent.So-called allergies, that is, a compound, once the role for human body skin, allergic body formation, in the next or after repeated exposure, not because how much contact, dermatitis can also occur.In this case, the job of the allergy compound should be interrupted.The development of allergy is complicated, the pudding experiment is adopted, the animal is studied.The American plastics industry association (SPI) introduced its own standards.
Chinese name: Diethyl toluene diamine(DETDA)
Diethyltoluenediamine packingļ¼ net weight 200KG/ galvanized iron drum (a small cabinet pallet loaded 16 tons), 1000KG/IB barrels (a small cabinet loaded 18 tons or 23 tons of ISOTANK).
Other toxic effects of crosslinking agents.In addition to the damage of aromatic amine and heterocyclic crosslinking agent to internal organs, the diphenylamine is carcinogenic and has been banned from production and use.Polyphenylenediamine, diamine diphenylsulfone, has been shown to be non-carcinogenic to many toxicologists, and negated the previous view.
The operation of crosslinking agent
1, the toxic low-crosslinking agent replaces the toxicity.
Improve the operating environment, consciously draw the operating area and non-operating area, automate as much as possible, close down, install ventilation and so on.
Strengthen labor protection, use protective glove, clothing and so on, avoid crosslinking agent and skin contact.
The operating area is cleaned in time and kept in good health.
Wash hands in time, face and other foreign skin, if eyes, throat and other organs are harmed, should ask the doctor to handle.
Copyright: Zhang Jia Gang YaRui Chemical co.,Ltd
Diethyl toluene diamine(DETDA) http://www.yaruichem.com
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