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More carbon 2 imide coating crosslinking agent
2017-4-11 22:29:59
More carbon 2 imide coating crosslinking agent. More carbon 2 imine structure of crosslinking agent was developed by the 1980 s. Purpose is to have n propyl organism crosslinking performance and low toxicity. Its characteristic is to quickly and resin containing carboxyl crosslinking (at 85 ℃ for 30 min crosslinking), and water reaction speed is quite slow. The paint film with good resistance to water and solvent resistance, and can improve the anti-corrosion performance of coatings.
Two imine carbon, N = C = N functional groups, is a kind of commonly used water loss. Generally by thiourea method for preparing or urea water loss, hydrolysis of urea derivatives. Mainly for the activation of carboxyl, amide and the formation of ester.
In organic synthesis, carbon 2 imine is a kind of commonly used agent, mainly used for activation of carboxyl, amide and the formation of ester. Reactions often join N - hydroxy benzene and three azole nitrogen or N - hydroxy succinimide, can improve the production rate, reduce the occurrence of adverse events. Two imine reaction with amine can also generate carbon guanidine.
Carboxylic acid and amine in carbon 2 imine loss of water condensation reaction under the diagram below. Carboxylic acid with carbon 1 2 O - imine reaction generated intermediates acyl thiourea 2, similar to the introduction of carboxylic acid ester base activation. Then 2 reaction with amine to produce the target product urea 3 and 4. 2 can generate reaction with another molecular carboxylic acid anhydride 5, has also been anhydride reaction with amine amides 3.
A byproduct of mainly 2 rearrangement of N - acylurea 6. Using low dielectric constant of solvent such as methylene chloride, chloroform) can reduce the generation of 6.
DCC (dicyclohexyl carbon imide) is one of the first to use carbon 2 imide, mostly used in peptide synthesis of peptide step. DCC as the reaction yield of water loss is very high, and is not expensive reagent.
But DCC has many disadvantages limit its applications:
Chinese name: Diethyl toluene diamine(DETDA)
Diethyltoluenediamine Uses:
The product is identical to Ethancure 100 and Lonza DETDA 80, DETDA is very effective polyurethane elastomer chain extender; also be used as polyurethane and epoxy resin curing agent, epoxy resin of an antioxidant, industrial oils and lubricants . In addition, also as intermediates in organic synthesis.Especially for the RIM (reaction injection molding), is important in the field of spray polyurea chain extender species. Also can be used for casting polyurethane elastomer (CPU) and a curing agent, epoxy curing agent, epoxy resin of antioxidants, lubricants and industrial oils other antioxidants.
By-products of N, N '- dicyclohexyl urea does not dissolve in water, generally with a filter to remove, but there are still a small amount of residual in solution, it is difficult to remove all;
2. DCC convenient than other solid phase peptide reagents, dicyclohexyl product urea is difficult to separate from the peptide resin;
3. The DCC can cause allergies.
DIC (N, N '- diisopropyl carbon imide) used as a substitute for DCC, compared with DCC has the following advantages:
1. DIC is liquid, easier to use;
2. The product of N, N '- diisopropyl urea soluble in most organic solvents, easily by solvent extraction to remove, DIC is so commonly used in solid state synthesis;
3. DIC leads to lower the possibility of allergies.
EDC (1 - (3 - dimethyl amino propyl) - 3-2 ethyl carbon imine hydrochloride) is a water soluble carbon 2 imide, in amide synthesis is used as carboxylic activation reagent, also used in activated phosphate groups, and protein and nucleic acid of crosslinking and immune accidentally even the making of things. When using the pH range of 4.0 to 4.0, with N - hydroxy succinimide (NHS) or N - hydroxy succinimide and, in order to improve coupling efficiency.
4 - dimethyl amine organic chemistry with EDC and catalyst pyridine (DMAP) result in the esterification of carboxylic acids and alcohols.
Copyright: Zhang Jia Gang YaRui Chemical co.,Ltd
Diethyl toluene diamine(DETDA) http://www.yaruichem.com
Two imine carbon, N = C = N functional groups, is a kind of commonly used water loss. Generally by thiourea method for preparing or urea water loss, hydrolysis of urea derivatives. Mainly for the activation of carboxyl, amide and the formation of ester.
In organic synthesis, carbon 2 imine is a kind of commonly used agent, mainly used for activation of carboxyl, amide and the formation of ester. Reactions often join N - hydroxy benzene and three azole nitrogen or N - hydroxy succinimide, can improve the production rate, reduce the occurrence of adverse events. Two imine reaction with amine can also generate carbon guanidine.
Carboxylic acid and amine in carbon 2 imine loss of water condensation reaction under the diagram below. Carboxylic acid with carbon 1 2 O - imine reaction generated intermediates acyl thiourea 2, similar to the introduction of carboxylic acid ester base activation. Then 2 reaction with amine to produce the target product urea 3 and 4. 2 can generate reaction with another molecular carboxylic acid anhydride 5, has also been anhydride reaction with amine amides 3.
A byproduct of mainly 2 rearrangement of N - acylurea 6. Using low dielectric constant of solvent such as methylene chloride, chloroform) can reduce the generation of 6.
DCC (dicyclohexyl carbon imide) is one of the first to use carbon 2 imide, mostly used in peptide synthesis of peptide step. DCC as the reaction yield of water loss is very high, and is not expensive reagent.
But DCC has many disadvantages limit its applications:
Chinese name: Diethyl toluene diamine(DETDA)
Diethyltoluenediamine Uses:
The product is identical to Ethancure 100 and Lonza DETDA 80, DETDA is very effective polyurethane elastomer chain extender; also be used as polyurethane and epoxy resin curing agent, epoxy resin of an antioxidant, industrial oils and lubricants . In addition, also as intermediates in organic synthesis.Especially for the RIM (reaction injection molding), is important in the field of spray polyurea chain extender species. Also can be used for casting polyurethane elastomer (CPU) and a curing agent, epoxy curing agent, epoxy resin of antioxidants, lubricants and industrial oils other antioxidants.
By-products of N, N '- dicyclohexyl urea does not dissolve in water, generally with a filter to remove, but there are still a small amount of residual in solution, it is difficult to remove all;
2. DCC convenient than other solid phase peptide reagents, dicyclohexyl product urea is difficult to separate from the peptide resin;
3. The DCC can cause allergies.
DIC (N, N '- diisopropyl carbon imide) used as a substitute for DCC, compared with DCC has the following advantages:
1. DIC is liquid, easier to use;
2. The product of N, N '- diisopropyl urea soluble in most organic solvents, easily by solvent extraction to remove, DIC is so commonly used in solid state synthesis;
3. DIC leads to lower the possibility of allergies.
EDC (1 - (3 - dimethyl amino propyl) - 3-2 ethyl carbon imine hydrochloride) is a water soluble carbon 2 imide, in amide synthesis is used as carboxylic activation reagent, also used in activated phosphate groups, and protein and nucleic acid of crosslinking and immune accidentally even the making of things. When using the pH range of 4.0 to 4.0, with N - hydroxy succinimide (NHS) or N - hydroxy succinimide and, in order to improve coupling efficiency.
4 - dimethyl amine organic chemistry with EDC and catalyst pyridine (DMAP) result in the esterification of carboxylic acids and alcohols.
Copyright: Zhang Jia Gang YaRui Chemical co.,Ltd
Diethyl toluene diamine(DETDA) http://www.yaruichem.com
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